The Human Upgrade: Biohacking for Longevity & Performance
Channel Details
The Human Upgrade: Biohacking for Longevity & Performance
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ -...
Recent Episodes
1487 episodes
Your Telomeres Are a Lie, Bats Beat Aging, Sleep Meds Ruin Mornings, CO's Silent Kill, and more... : 1431
This week’s stories:
Smartphone App Catches What Sleep Trackers Miss
A 2026 trial found that suvorexant, a popular prescri...
Your Penis Is a Longevity Organ (Here's How to Hack It) : 1430
Testosterone levels in 40-year-old men are 30 percent lower than their fathers, and most doctors still have no idea what to do about it.
...
AI Expert Says: Humans Are Just Mystical Meat Robots : 1429
What if understanding how AI thinks could reveal uncomfortable truths about how your own brain works, and give you powerful tools to make smarter deci...
How I Finally FIXED My Terrible Sleep After 18 Years : 1428
Block toxic light with these glasses: https://truedark.com/discount/DAVETUBE
Think 8 hours of sleep is enough? Think again. I used...
WW3 Doomscrolling, 5 Minute Sleep Hack, Diet Wars, Dopamine Supplements : 1427
This week’s stories:
Healthy Diets That Offset "Bad Genes"
A major UK Biobank study of over 100,000 people found that foll...
Your Brain Is 0.5% Plastic (Here’s How to Flush It) : 1426
Microplastics are invading your brain, blood, hormones, and fat tissue, and most people have no idea how deep the damage goes. In this episode, Host D...
Why Are Hackers Microdosing “Sex Drugs” Now? : 1425
Most doctors treat the average patient. But you are not average, and this episode gives you the precision medicine blueprint to treat yourself like th...
A-List Celebrities' Anti-Aging Hack to Look 30 At 50 (Drug-free) : 1424
What if the secret to living longer wasn't locked in a lab, but hiding in plain sight? And what could lobsters possibly teach us about staying young?<...
Mexican Cartel Biohacking, Google Anti-Aging Breakthrough, Measles Is Back, Age Reversal In 2026 : 1423
This week’s stories:
Sinclair’s This Is the Test: Are we about to see age reversal in humans?
At the World G...
The Secret to Staying DANGEROUS After 50 : 1422
Peptides can change how you heal, lean out, build muscle, and age, but only if you stop taking influencer advice and start thinking like a scientist. ...
The Home Laser That Reverses Skin Age By 20 Years : 1421
Your skin is not just a cosmetic surface. It’s a living organ that responds to signals, and the right light signal can flip your biology into repair m...
I Tested The Most Dangerous Viral Brain Hack : 1420
Most people try to fix brain fog and focus issues with caffeine or nootropics, but those approaches only mask the problem.
This vi...
Plastic in Your Testicles, AI Sleep Scans, The 29% Weight Loss Drug : 1419
This episode covers:
• Microplastics Are Destroying Male Fertility and Metabolism
New research is putting microplastics in...
Change Your Morning, Change Your Life – Hal Elrod : 1418
Meet a man who makes miracles happen. Today, we revist my conversation with Hal Elrod, author of the international bestseller The Miracle Morning and...
The Secret to Looking Younger is in Mushrooms (And Chocolate?) : 1417
Your gray hair, thinning lashes, brain fog, and that low energy feeling after 30 might all trace back to one thing: falling NAD and stressed mitochond...
Low Testosterone Starts In Your Eyes (Avoid This Before Bed) : 1416
https://truedark.com/discount/DAVETUBE
Most people believe testosterone declines simply because of age. That explanation is easy,...
Jet Lag Superdrug, 25% Dementia Drop, Coffee Brain Aging, Kratom Shakeup : 1415
This episode covers:
• Mic-628 Could Reset Your Body Clock and Cut Jet Lag in Half
A new circadian drug candidate, Mic-628...
Turn Off Your WiFi Tonight and See What Happens to Your Sleep : 1414
Your phone, your lighting, and your WiFi can mess with your sleep and energy more than your diet, and this episode shows you the simplest fixes that a...
The Secret Peptides and Underground Compounds Doctors Won’t Talk About : 1413
What if the line between “medicine” and “forbidden” has nothing to do with safety and everything to do with permission? This episode gives you a clear...
Why Your Muscles Break Down After 40 (Do This To Reverse It) : 1412
Your muscles play a far bigger role in aging than most people realize. As you get older, the energy factories inside your muscle cells begin to break...
Biohackers in the Epstein Files, Generic GLP-1s, Continuous Ketone Monitors, and more... : 1411
This episode covers:
• Longevity Influence In The Epstein Files
A new DOJ document release tied to the Epstein investigati...
Why 18-Year-Olds Wake Up Fresh (And You Don't) : 1410
18-year-olds wake up fresh because their repair system still works. This episode shows you how stem cell decline quietly drives fatigue, inflammation,...
STOP Intermittent Fasting If You Want to Stay Young : 1409
STOP intermittent fasting if you think it automatically keeps you young. In this episode, you’ll learn why short-term fasting results can mislead long...
Aging Starts In Your Legs (Here’s The Fix) : 1408
Most people think aging starts with wrinkles, gray hair, or memory loss. It doesn’t.
Aging starts when your legs begin to weaken,...
The Nobel Prize Molecule That Nearly Doubles Lifespan : 1407
In the late 1990s, a strange carbon molecule quietly delivered the single longest lifespan extension ever recorded in mammals. The rats lived about 90...
Meet the Governor Who Wants Humans to Become Cyborgs : 1406
Aging is not something Zoltan Istvan plans to accept quietly. He wants to treat death like a technical bug, rewrite the rules of biology, and turn Cal...
Your Butt is a Longevity Organ (Here’s how to train it!) | Gabrielle Lyon : 1405
Your butt is not about aesthetics. It is a longevity organ that directly impacts metabolism, brain optimization, resilience, and how long you stay str...
The Natural Ozempic In Your Gut (Eat THIS To Switch It On) : 1404
Your gut already has its own version of Ozempic, and it’s been doing this job long before injections existed.
In this video, I exp...
Biohacking News Weekly Update : 1403
This episode covers:
• Real Food Reset in U.S. Dietary Policy
The new Dietary Guidelines for Americans 2025–2030 put real...
This Brain Trick Feels Like Cheating (Do THIS) : 1402
Most brain decline, mood instability, and impulsive behavior start with a breakdown in how the brain’s immune cells produce and use energy. This episo...
Inside the Mind of the Mad Scientist Rewriting Aging : 1401
Your body does not fail all at once. Aging starts when cells quietly shift into survival mode and never come back out. In this episode, you go inside...
I Lost 100 Pounds Of Fat By Drinking Fat (Just Do This) : 1400
One freezing sip on a Tibetan mountain rewired his hunger, silenced cravings, and unlocked a kind of fat-burning “switch” no doctor ever mentioned. Wh...
The Superbrain Drug Politicians Use To Outsmart Everyone : 1399
This drug has been misunderstood for decades, and that confusion is costing people focus, learning speed, and cognitive performance. In this episode, ...
Why 65% of People SUCK at Modern Relationships : 1398
Most people are struggling in modern relationships, and it is not because they are broken. It is because the systems around them are. In this episode,...
The 12 Greatest Mood Boosters on Earth : 1397
Mood, motivation, and emotional resilience are not personality traits. They are biological systems. In this episode, you’ll get the 12 greatest mood b...
I Cracked The Code To Staying Lean In My 50s (Here's How) : 1396
Most people think fasting is just about skipping breakfast. But what if 72 hours without food could actually reverse aging?
In thi...
Reversing The American Food Pyramid | Calley Means : 1395
Back in 2024 with Calley Means at South by Southwest, we sat down and talked about his mission to flip the old American food pyramid upside down for t...
The Willpower Drug: How to Supplement Discipline : 1394
Creatine is a hot subject right now, but I’m guessing you might not know as much about it as you could. Well step into a new creatine masterclass with...
How Long Can Humans Really Live… (with Dan Buettner) : 1393
You’re about to hear one of the most honest longevity conversations ever recorded. This co hosted episode brings together two longevity leaders with o...
This Legal Boner Pill Is Hiding A Future Heart Attack : 1392
Most men think ED is just a performance issue. It’s not. It’s one of the earliest warning signs of cardiovascular decline and it often appears years b...